RISE Kisspeptin-10 is a precision research spray delivering the biologically active C-terminal decapeptide fragment of the kisspeptin family. 100mcg per 0.1ml spray — researched for its role as an upstream regulator of the hypothalamic-pituitary-gonadal axis via GPR54 receptor activation, spanning reproductive neuroendocrinology, metabolic research, and hormonal signalling investigation.
Compound: Kisspeptin-10 (active C-terminal decapeptide fragment · KISS1 gene encoded)
CAS: 374683-25-7
Concentration: 100mcg per 0.1ml spray
Total content: 15mg per unit
Volume: 10ml — approximately 100 applications
Purity: ≥99% by HPLC-MS — independently verified
Container: MIRON violet glass, metered-dose spray pump actuator
Format: Pre-constituted spray — ready for research application.
Active substance:
Kisspeptin-10 (H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂) · 100mcg per 0.1ml actuation
Excipients:
Bacteriostatic Water
Sodium Chloride
Refrigerate at 2–8°C immediately upon receipt.
Do not freeze.
Keep away from direct light and heat sources.
Store upright in original container.
Use within 30 days of opening.
Kisspeptin is temperature-sensitive — handle with particular care throughout receipt and storage.
Do not use if the solution appears cloudy, discoloured, or contains visible particles.
Dispatched within 48 hours of payment confirmation on business days. Shipped via Royal Mail Tracked 24 — next business day delivery from point of dispatch. A tracking reference will be provided in your dispatch notification email.
Free shipping on orders of £85 or over.
Kisspeptin exists in several biologically active isoforms — Kisspeptin-54, Kisspeptin-14, Kisspeptin-13, and Kisspeptin-10 — all derived from the same KISS1 gene precursor through proteolytic cleavage. Kisspeptin-10 is the shortest active fragment, retaining the C-terminal decapeptide sequence responsible for full GPR54 receptor activation. It is the most studied isoform in research settings due to its compact structure, receptor specificity, and stability compared to the full-length Kisspeptin-54 precursor. RISE specifies Kisspeptin-10 to ensure compound precision and research consistency.
Kisspeptin-10 sits upstream of the primary hormonal cascade — activating GnRH neurons via GPR54 receptor binding rather than acting directly on gonadal hormone production. This upstream position makes it a compound of distinct research significance for investigators studying neuroendocrine regulation at the signalling level. Its role as a master regulator of the hypothalamic-pituitary-gonadal axis has been confirmed through landmark studies including Seminara et al. (2003) in the New England Journal of Medicine and de Roux et al. (2003) in the Proceedings of the National Academy of Sciences — both identifying GPR54 as essential for puberty onset and gonadotropin regulation.
MIRON violet glass blocks the full visible light spectrum while selectively transmitting UV-A and infrared wavelengths. Research indicates this has a biophotonic preservation effect — slowing the molecular degradation of light-sensitive compounds more effectively than standard amber glass. It is used in high-end pharmaceutical and nutraceutical packaging. RISE specifies MIRON glass as a deliberate formulation decision to protect compound integrity from manufacture through to end use.
Every RISE product ships with a unique lot number printed on the bottle label. Enter your lot number at rise-labs.co.uk/coa to access the batch-specific Certificate of Analysis issued by our independent third-party testing laboratory. The CoA includes HPLC purity percentage, mass spectrometry identity confirmation, and the issuing laboratory’s details for independent verification.
RISE supplies research-grade peptide compounds for laboratory and scientific investigation only. Our products are not medicines, supplements, or consumer health products.
